1. It is now over 30 years since health authorities set dietary targets in the UK. By 2003, the 25% reduction in SFA had been achieved and there had been a decrease in the amount of fat consumed. Despite this, the incidence of obesity and diabetes has continued to increase. In fact, it now emerges that there never was any reliable evidence to support these public policy initiatives in the first place. An evaluation of the studies available prior to 1983 in which the fat content of the diet was altered in line with the recommendations was published in 20154. Dr. Zoë Harcombe and colleagues found that even though the TC was reduced by the dietary intervention there was no difference in ACM.
2. The most compelling reason for believing that insulin, or possibly some other hormone, plays a central role in the development of heart disease is the multiplicity of changes that accompany the disease. It is difficult to see how these could occur unless there was some disturbance of the hormone levels. Yudkin considered that insulin was the most likely hormone to be involved. He suggested that a consistently high-sugar diet meant that there was a persistently high demand for the pancreas to produce insulin. Because insulin has many different functions, the excess may well be deleterious in other ways, such as upsetting the established hormone balance.